858187-20-9Relevant academic research and scientific papers
Enzymatic sulfation of phenolic hydroxy groups of various plant metabolites by an arylsulfotransferase
Van Der Horst, Michael A.,Hartog, Aloysius F.,El Morabet, Rabab,Marais, Arthur,Kircz, Menzo,Wever, Ron
supporting information, p. 534 - 541 (2015/01/30)
The bacterial arylsulfate sulfotransferase (AST) from Desulfitobacterium hafniense was used as a catalytic tool to derivatize poorly soluble aromatic compounds (polyphenols). As examples, we sulfated the natural occurring compounds p-coumaric acid, 6-hydr
Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites
Hoshino, Juma,Park, Eun-Jung,Kondratyuk, Tamara P.,Marler, Laura,Pezzuto, John M.,Van Breemen, Richard B.,Mo, Shunyan,Li, Yongchao,Cushman, Mark
experimental part, p. 5033 - 5043 (2010/09/16)
Five resveratrol sulfate metabolites were synthesized and assessed for activities known to be mediated by resveratrol: inhibition of tumor necrosis factor (TNF) α induced NFkB activity, cylcooxygenases (COX-1 and COX-2), aromatase, nitric oxide
Soluble polyphenols: Synthesis and bioavailability of 3,4′,5-tri(α-d-glucose-3-O-succinyl) resveratrol
Biasutto, Lucia,Marotta, Ester,Bradaschia, Alice,Fallica, Mauro,Mattarei, Andrea,Garbisa, Spiridione,Zoratti, Mario,Paradisi, Cristina
supporting information; experimental part, p. 6721 - 6724 (2010/06/12)
We report the development of a chemical modification method of general applicability to polyphenols, which increases solubility to influence absorption. Glucosyl groups were added to the resveratrol kernel via a succinate linker, yielding 3,4′,5-tri-(α-d-
