85825-82-7

Upstream product

• 138279-26-2 (+)-methyl pivaloyloxymethyl 1,4-dihydro-2,6-dimethyl-4-phenyl-3,5-pyridinedicarboxylate 
• 138279-13-7 bis(pivaloyloxymethyl) 1,4-dihydro-1-(methoxymethyl)-2,6-dimethyl-4-phenyl-3,5-pyridinedicarboxylate 
• 70677-78-0 dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate 
• 100-52-7 benzaldehyde 
• 138279-17-1 1-Methoxymethyl-2,6-dimethyl-4-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid mono-(2,2-dimethyl-propionyloxymethyl) ester 
• 138279-23-9 (+)-methyl pivaloyloxymethyl 1,4-dihydro-2,6-dimethyl-1-methoxymethyl-4-phenyl-3,5-pyridinedicarboxylate 
• 141600-86-4 1-Methoxymethyl-2,6-dimethyl-4-phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 

Relevant academic research and scientific papers

Synthesis and photoluminescent properties of novel 1,4-dihydropyridine derivatives

Six new 1,4-dihydropyridine derivatives were synthesized, the UV-vis absorption and photoluminescence of these compounds were also studied. All the compounds exhibited strong blue emissions. (λem:436-451nm). The results showed that the absorption maxima of the compounds vary from 332 to 345nm depending on the group bonded to dihydropyridines rings.

Synthesis and antioxidant activity of a series of novel 3-chalcone-substituted 1,4-dihydropyridine derivatives

New 3-chalcone-substituted 1,4-dihydropyridine (DHP) derivatives have been synthesized based on dimethyl or diethyl 2,6-dimethyl-4-phenyl-1,4-DHP-3,5- dicarboxylate. Their structures were confirmed by IR, 1H NMR, 13C NMR, and elemental analyses. The synthesized compounds were also screened for antioxidant properties.

Acyloxymethyl as an activating group in lipase-catalyzed enantioselective hydrolysis. A versatile approach to chiral 4-aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylates

The first practical syntheses of chiral 4-aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylates, which are attractive compounds as new calcium antagonists, were realized by lipase-catalyzed enantioselective hydrolysis of the acyloxymethyl esters. The monoesters obtained were revealed to have high optical purity and demonstrated to be useful chiral synthons.