85828-15-5

Upstream product

• 73814-78-5 (2R,3S,4S)-1-Benzyloxy-2,4-dimethyl-hex-5-en-3-ol 
• 98315-18-5 (1R,3S,4S,5R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-1,4-dimethyl-8-methylene-2,9-dioxa-bicyclo[3.3.1]nonan-6-ol 
• 98315-11-8 (2S,3R,4R,5R)-6-Benzyloxy-2,4-dihydroxy-3,5-dimethyl-hexanenitrile 
• 71011-64-8 (2R,3S)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-3-methyl-oxirane 
• 98315-17-4 (5R,6S,7S,8S)-9-Benzyloxy-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-6,8-dimethyl-2-(2,5,5-trimethyl-[1,3]dioxan-2-yl)-non-1-en-4-ol 
• 98315-15-2 (2S,3R,4R,5R)-6-Benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexanal 
• 98315-14-1 (2S,3R,4R,5R)-6-Benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexanenitrile 
• 98315-10-7 (3S,4S,5R)-6-Benzyloxy-4-hydroxy-3,5-dimethyl-hexanenitrile 
• 98315-16-3 2-(1-Bromomethyl-vinyl)-2,5,5-trimethyl-[1,3]dioxane 
• 98315-30-1 2-isopropenyl-2,5,5-trimethyl-1,3-dioxane 
• 85880-74-6 (1R,2S,3R,4R)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentan-1-ol 
• 85828-12-2 (2S,3S,4S)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanal 
• 14920-89-9 2,3-dimethylfuran 
• 85828-13-3 (1S,2S,3R,4R)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentan-1-ol 

Downstream Products

• 97859-87-5 <1R*-<1β,2α,4α,6β,7α,8β(1E,2E,4E,6R*)>>-1-(2,4-dimethoxybenzyl)-3-<1-hydroxy-4-methyl-6-(1,2,7-trimethyl-5-oxo-3,9,10-trioxatricyclo<4.3.1.0(2,4)>dec-8-yl)-2,4-heptadienylidene>-2,4-pyrrolidinedione 

Relevant academic research and scientific papers

Total Synthesis of (+/-)-Tirandamycin A

A convergent, 12-step synthesis of racemic tirandamycin A is described.The key features of the synthesis are preparation of the 2,9-dioxabicyclononane system of the natural product by oxidation of furfuryl alcohol 8a and attachment of the 3-acyl te

ACID-CATALYZED REARRANGEMENT OF PYRAN DERIVATIVES. AN APPROACH TO THE STEREOSELECTIVE SYNTHESIS OF 1,3-DIOL DERIVATIVES

Peracid oxidation and HF-catalyzed treatment of furfuryl alcohol derivatives afford lactone products arising from a highly stereoselective rearrangement process.The lactone serve as precursors of highly functionalized anti-1,3-diol derivatives.

Synthesis of the dioxabicyclononane unit of tirandamycin

A seven-step synthesis of (±)-3b, an advanced, common intermediated for construction of the dioxabicyclononane units of both tirandamycin and streptolydigin is described. Conversion of 3b to the fully developed fragment of tirandamycin is also reported.