858341-24-9Relevant academic research and scientific papers
A highly diastereomerically enriched, silyl-substituted alkyl lithium, configurationally stable at room temperature
Strohmann, Carsten,Abele, Bors C.,Lehmen, Klaus,Schildbach, Daniel
, p. 3136 - 3139 (2005)
The opening or blocking of a coordination site at the lithium center (for example by attachment of THF, see picture; left) leads to diastereodivergent courses in the reactions of a highly diastereomerically enriched alkyl lithium with Me3SnCl. At room temperature in noncoordinating solvents the reagent is configurationally stable and epimerizes in the presence of THF. (Chemical Equation Presented)
