18407-40-4Relevant articles and documents
Synthesis and structural study of precursors of novel methylsilanediols by IR and Raman spectroscopies, single-crystal X-ray diffraction and DFT calculations
Rodríguez Ortega,Docampo,Thomas,Montejo,Marchal Ingraín,Wilson,López González
, p. 828 - 834 (2014)
On the way towards the development of a synthetic route aimed at obtaining new methylsilanediol derivatives with an aminocarbonyl group in β to silicon (which may have a potential biological interest), we have synthesized, isolated and purified five diphe
Palladium-Catalyzed β-Elimination of Aminoboranes from (Aminomethylsilyl)boranes Leading to the Formation of Silene Dimers
Ohmura, Toshimichi,Nishiura, Hiroki,Suginome, Michinori
supporting information, p. 4298 - 4304 (2017/11/20)
Silylboronic esters bearing a N,N-dialkylaminomethyl group on the silicon atoms were synthesized and used in palladium-catalyzed reactions. Five silylboronic esters were synthesized through a reaction of the [(N,N-dialkylaminomethyl)diorganosilyl]lithiums
THE PREPARATION AND CHEMISTRY OF (R)-(1-NAPHTYL)PHENYLMETHYLSILYLMETHYLLITHIUM: STEREOCHEMISTRY AT SILICON IN THE ELIMINATION OF β-HYDROXYSILANES
Larson, Gerald L.,Prieto, J. Antonio,Ortiz, Edgardo
, p. 3781 - 3790 (2007/10/02)
(R)-(1-naphthyl)phenylmethylsilylmethyllithium has been prepared from 1-naphthylphenylmethylsilylmethyltri-n-butyltin, which is in turn prepared in four steps from (R)-(1-naphthyl)phenylmethylsilane.The title lithium reagent was reacted with benzaldehyde, pivaldehyde, acrolein and 2-methylcyclohexanone to produce the corresponding β-hydroxysilanes in good yield, but with only a 3-4percent diastereomeric excess.Unfortunately, these diastereomers proved impossible to separate.Model studies employing the methyldiphenylsilyl group showed that these β-hydroxysilanes could be protiodesilylated to give the corresponding methyl alcohol.The products from the adduct with pivaldehyde and acrolein were used to investigate the stereochemistry at silicon of the β-hydroxysilanes.This was found to occur with inversion of configuration at silicon when the elimination is carried out with boron fluoride etherate, sulfuric acid or acetic acid/sodium acetate, but with retention of configuration when carried out with potassium hydride.