858346-81-3

Upstream product

• 858346-65-3 2-{(2R,6S)-6-[(2S,4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-methyl-4-trimethylsilanyloxy-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 
• 858346-77-7 2-[(2R,6S)-6-((2S,4R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-5-methyl-7-{(2S,6S)-6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-4-trimethylsilanyloxy-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 404890-44-4 2-{(2R,6S)-6-[(2R,4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2,4-dihydroxy-5-methyl-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 
• 404890-72-8 2-{(2R,6S)-6-[(4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-4-hydroxy-5-methyl-2-oxo-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 
• 851594-64-4 trifluoromethanesulfonic acid 4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl ester 
• 858346-79-9 2-[(2R,6S)-6-((2R,4R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-methyl-7-{(2S,6S)-6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 851594-70-2 2-{(2R,6S)-6-[(2R,4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-5-methyl-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 

Relevant academic research and scientific papers

A concise synthesis of (+)-SCH 351448

(Chemical Equation Presented) We describe a highly convergent synthetic approach to the natural product (+)-SCH 351448 (1) - a hexane-soluble heptacoordinate monosodium salt of a C2-symmetrical macrocyclic dilactone. Our approach implements a p