404890-44-4

Upstream product

• 404890-78-4 (S)-4-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2-methyl-butan-1-ol 
• 404890-70-6 Thiocarbonic acid O-[(1R,2S)-1-((2S,6R)-6-allyl-tetrahydro-pyran-2-ylmethyl)-3-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2-methyl-3-oxo-propyl] ester O-phenyl ester 
• 404890-69-3 (2S,3R)-4-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-1-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-hydroxy-2-methyl-butan-1-one 
• 404890-71-7 (S)-4-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-1-((1R,5S,7S)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2-methyl-butan-1-one 
• 404890-57-9 (E)-(R)-3-Hydroxy-2,2-dimethyl-9-oxo-dec-7-enoic acid benzyl ester 
• 404890-59-1 2-Methyl-2-[(2R,6R)-6-(2-oxo-propyl)-tetrahydro-pyran-2-yl]-propionic acid benzyl ester 
• 404890-50-2 (R)-3-Acryloyloxy-2,2-dimethyl-hex-5-enoic acid benzyl ester 
• 404890-52-4 2-Methyl-2-((R)-6-oxo-tetrahydro-pyran-2-yl)-propionic acid benzyl ester 
• 404890-54-6 2-((R)-6-Hydroxy-tetrahydro-pyran-2-yl)-2-methyl-propionic acid benzyl ester 
• 404890-51-3 2-methyl-2-(6-oxo-3,6-dihydro-2H-pyran-2-yl)-propionic acid benzyl ester 
• 404890-49-9 (R)-3-Hydroxy-2,2-dimethyl-hex-5-enoic acid benzyl ester 
• 404890-66-0 2-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-ethanol 
• 404890-67-1 ((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-acetaldehyde 
• 97518-80-4 benzyl 2,2-dimethyl-3-oxopropanoate 

Downstream Products

• 851594-70-2 2-{(2R,6S)-6-[(2R,4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-5-methyl-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 
• 858346-80-2 2-[6-(2-(tert-butyl-dimethyl-silanyloxy)-5-methyl-7-{6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-4-trifluoroacetoxy-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 858346-77-7 2-[(2R,6S)-6-((2S,4R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-5-methyl-7-{(2S,6S)-6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-4-trimethylsilanyloxy-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 858346-79-9 2-[(2R,6S)-6-((2R,4R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-methyl-7-{(2S,6S)-6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 858346-81-3 2-[(2R,6S)-6-((2R,4R,5S)-2,4-Dihydroxy-5-methyl-7-{(2S,6S)-6-[3-(4-oxo-2,2-diphenyl-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 858346-78-8 2-[(2R,6S)-6-((2R,4R,5S)-2-(tert-Butyl-dimethyl-silanyloxy)-7-{(2S,6S)-6-[3-(2,2-dimethyl-4-oxo-4H-benzo[1,3]dioxin-5-yl)-propyl]-tetrahydro-pyran-2-yl}-4-hydroxy-5-methyl-heptyl)-tetrahydro-pyran-2-yl]-2-methyl-propionic acid benzyl ester 
• 858346-65-3 2-{(2R,6S)-6-[(2S,4R,5S)-7-((2S,6R)-6-Allyl-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxy)-5-methyl-4-trimethylsilanyloxy-heptyl]-tetrahydro-pyran-2-yl}-2-methyl-propionic acid benzyl ester 

Relevant academic research and scientific papers

A concise synthesis of (+)-SCH 351448

(Chemical Equation Presented) We describe a highly convergent synthetic approach to the natural product (+)-SCH 351448 (1) - a hexane-soluble heptacoordinate monosodium salt of a C2-symmetrical macrocyclic dilactone. Our approach implements a p

Synthesis of the C1-C21 (C1'-C21') fragment of the dimeric polyketide natural product SCH 351448.

[structure: see text] A convergent, stereoselective assembly of the C1-C21 (C1'-C21') fragment of SCH 351448, a 28-membered bis-lactone natural product, has been developed. A highly efficient approach to this fragment assembles 75% of the carbon skeleton