85849-33-8 Usage
General Description
(+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS[BIS(2-METHYLPHENYL)PHOSPHINO]BUTANE is a chemical compound used in organic synthesis as a chiral ligand for transition metal-catalyzed reactions. It is a complex molecule comprised of multiple functional groups, including isopropylidene, dihydroxy, and bis(2-methylphenyl)phosphino groups, which contribute to its complex and versatile reactivity. (+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS[BIS(2-METHYLPHENYL)PHOSPHINO]BUTANE has been utilized in various asymmetric catalytic reactions, such as hydrogenation, hydroformylation, and allylic alkylation, due to its ability to selectively bind with transition metals and facilitate enantioselective transformations. Additionally, (+)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS[BIS(2-METHYLPHENYL)PHOSPHINO]BUTANE has been studied for its potential applications in pharmaceutical synthesis and material science, making it a valuable compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 85849-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,8,4 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 85849-33:
(7*8)+(6*5)+(5*8)+(4*4)+(3*9)+(2*3)+(1*3)=178
178 % 10 = 8
So 85849-33-8 is a valid CAS Registry Number.
85849-33-8Relevant articles and documents
Rhodium-Catalyzed Enantioselective Radical Addition of CX4 Reagents to Olefins
Chen, Bo,Fang, Cheng,Liu, Peng,Ready, Joseph M.
supporting information, p. 8780 - 8784 (2017/07/17)
We describe the synthetically useful enantioselective addition of Br?CX3 (X=Cl or Br) to terminal olefins to introduce a trihalomethyl group and generate optically active secondary bromides. Computational and experimental evidence supports an asymmetric atom-transfer radical addition (ATRA) mechanism in which the stereodetermining step involves outer-sphere bromine abstraction from a [(bisphosphine)RhIIBrCl] complex by a benzylic radical intermediate. This mechanism appears unprecedented in asymmetric catalysis.
