85863-92-9Relevant academic research and scientific papers
Quinolizidine Alkaloid Synthesis via the Intramolecular Imino Diels-Alder Reaction. epi-Lupinine and Cryptopleurine
Bremmer, Martin L.,Khatri, Nazir A.,Weinreb, Steven M.
, p. 3661 - 3666 (2007/10/02)
A totally stereoselective total synthesis of epi-lupinine (1) has been developed that starts with methyl sorbate (6).Alkylation of 6 with bromide 8 gave diene 10, which was elaborated into the imino Diels-Alder precursor 17.Thermolysis of 17 provided excl
A STEREOSELECTIVE TOTAL SYNTHESIS OF EPI-LUPININE
Bremmer, Martin L.,Weinreb, Steven M.
, p. 261 - 264 (2007/10/02)
An intramolecular imino Diels-Alder reaction has been used both to construct the quinolizidine ring system and to set the proper relative stereochemistry of the alkaloid epi-lupinine (1).
