85863-93-0

Basic information

• Product Name: 5-hydroxy-2,2,11-trimethyl-2,11-dihydro-6H-chromeno[7,6-b][1,8]naphthyridin-6-one
• CAS NO: 85863-93-0
• Molecular Formula: C₁₈H₁₆N₂O₃
• Molecular Weight: 308.3312
• Mol File: 85863-93-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 548.6°C at 760 mmHg
• Flash Point: 285.6°C
• Density: 1.312g/cm³
• Vapor Pressure: 1.2E-12mmHg at 25°C
• Refractive Index: 1.642
• CAS DataBase Reference: 5-hydroxy-2,2,11-trimethyl-2,11-dihydro-6H-chromeno[7,6-b][1,8]naphthyridin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-2,2,11-trimethyl-2,11-dihydro-6H-chromeno[7,6-b][1,8]naphthyridin-6-one(85863-93-0)
• EPA Substance Registry System: 5-hydroxy-2,2,11-trimethyl-2,11-dihydro-6H-chromeno[7,6-b][1,8]naphthyridin-6-one(85863-93-0)

Safety Data

• Hazardous Substances Data: 85863-93-0(Hazardous Substances Data)

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 85864-01-3 6,8-dimethoxy-10-methylbenzo<1,8>naphthyridin-5(10H)-one 
• 85864-00-2 6,8-dimethoxybenzo<1,8>naphthyridin-5(10H)-one 
• 85864-05-7 2-(3',5'-dimethoxyanilino)nicotinic acid 
• 85864-03-5 6,8-dihydroxy-10-methylbenzo<1,8>naphthyridin-5(10H)-one 
• 2942-59-8 2-chloronicotinic acid 
• 85864-04-6 8-(1',1'-dimethylprop-2-ynyloxy)-6-hydroxy-10-methylbenzo<1,8>naphthyridin-5(10H)-one 
• 1111-97-3 3-chloro-3-methylbut-1-yne 

Relevant articles and documents

Synthesis of Acronycine Isosters

The synthesis of the two key intermediates 6,8-dihydroxy-10-methylbenzonaphthyridin-5(10H)-one (4b) and 6,8-dihydroxy-5H-benzopyranopyridin-5-one (4d) for the synthesis of acronycine isosteres is described.The condensation of (4b) with 3-chloro-3-methylbut-1-yne afforded three isomers (5), (6), and (7), from which it was possible to distinguish between the angular isomer (5) and the linear isomer (6) with the aid of 13C n.m.r. spectroscopy.The condensation of (4d) with 3-chloro-3-methylbut-1-yne yielded only one product (8).The action of dimethyl sulphate on 6-hydroxy-3,3-dimethyl-3H-pyranochromenopyridin-7-one (8) as well as on 6,8-dimethoxy-5H-benzopyranopyridin-5-one (3b) is also reported.