85864-09-1

Basic information

• Product Name: 6-cyano-1H-indole-2-carboxylic acid
• Synonyms: 6-cyano-1H-indole-2-carboxylic acid;1H-Indole-2-carboxylic acid, 6-cyano-
• CAS NO: 85864-09-1
• Molecular Formula: C₁₀H₆N₂O₂
• Molecular Weight: 186.16684
• EINECS: -0
• Mol File: 85864-09-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-cyano-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-cyano-1H-indole-2-carboxylic acid(85864-09-1)
• EPA Substance Registry System: 6-cyano-1H-indole-2-carboxylic acid(85864-09-1)

Safety Data

• Hazardous Substances Data: 85864-09-1(Hazardous Substances Data)

Usage

General Description

6-cyano-1H-indole-2-carboxylic acid is a chemical compound with the molecular formula C10H7N2O2. It is a derivative of indole and contains a carboxylic acid and a cyano group. 6-cyano-1H-indole-2-carboxylic acid is a common intermediate in the synthesis of pharmaceuticals and other biologically active compounds. It has been used in the development of drugs for the treatment of various diseases, including cancer and neurological disorders. Its chemical structure and properties make it a valuable building block for the production of a wide range of important organic compounds.

Upstream product

• 104-85-8 para-methylbenzonitrile 
• 104291-83-0 6-Cyanindol-2-carbonsaeure-methylester 
• 105191-34-2 3-(4-cyano-2-nitro-phenyl)-2-oxo-propionic acid ethyl ester 
• 939-79-7 4-cyano-2-nitrotoluene 
• 104291-81-8 ethyl 6-cyano-1H-indole-2-carboxylate 

Downstream Products

• 15861-36-6 1H-Indole-6-carbonitrile 
• 147920-12-5 1-[(6-cyano-2-indolyl)carbonyl]-4-[3-(isopropylamino)-2-pyridinyl]piperazine 
• 199609-40-0 6-(Benzyloxycarbonylamino-imino-methyl)-1H-indole-2-carboxylic acid 
• 259150-24-8 tert-butyl trans-[4-(6-amidinoindole-2-carboxamido)cyclohexyloxy]acetate 
• 174775-27-0 {4-[(6-cyano-1H-indole-2-carbonyl)-amino]-cyclohexyloxy}-acetic acid tert-butyl ester 

Relevant articles and documents

POLYHETEROCYCLIC COMPOUNDS AS METTL3 INHIBITORS

The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity: X-Y-Z (I) wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity is implicated.

N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS

The present invention relates to compounds of formula (I) : and pharmaceutically acceptable salts thereof, wherein R1and R2 are various ring systems. The invention also relates to pharmaceutical compositions comprising these compound

Preparation and pharmacological evaluation of novel glycoprotein (Gp) IIb/IIIa antagonists. 2. Condensed heterocyclic derivatives

A novel series of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists with condensed heterocycles as their basic core was synthesized. In an in vitro assay, trans-4-(5-amidinobenzofuran-2- carboxamido)cyclohexyl]oxyacetic acid 17e and trans-3-[4-(5-