858644-28-7Relevant academic research and scientific papers
Copper-Catalyzed Microwave-Expedited Oxyphosphorylation of Alkynes with Diethyl Phosphite and t-Butyl Hydroperoxide Synthesis of Densely Functionalized Phosphonylated Indenones
Maciás-Benítez, Pablo,Sierra-Padilla, Alfonso,Tenorio, Manuel J.,Moreno-Dorado, F. Javier,Guerra, Francisco M.
, p. 16409 - 16424 (2021/11/16)
Treatment of alkynes with diethyl phosphite and t-butyl hydroperoxide in the presence of [Cu(MeCN)4]BF4 under microwave irradiation produced the oxyphosphorylation of the triple bond, giving rise to the corresponding β-ketophosphonates in moderate-to-good yields. When the triple bond was conjugated to a carbonyl group bearing an aromatic ring, it led to the cyclization of the resulting ketone intermediate, producing eventually different phosphonylated indenones.
Palladium-Catalyzed Oxidative Cyclization for the Synthesis of Indolyl/Pyrrolyl 3-Phosphonates
Mishra, Aniket,Deb, Indubhusan
, p. 2267 - 2272 (2016/07/29)
Imino-/enaminophosphonates derived from amines and diethyl phenacyl phosphonates undergo oxidative cyclization via C H bond activation catalyzed by palladium chloride to provide a convenient route for the synthesis of substituted indol-3-yl and pyrrol-3-yl phosphonates. (Figure presented.) .
An efficient preparation of β-aryl-β-ketophosphonates by the TFAA/H3PO4-mediated acylation of arenes with phosphonoacetic acids
Luke, George P.,Seekamp, Christopher K.,Wang, Zhe-Qing,Chenard, Bertrand L.
, p. 6397 - 6400 (2008/12/21)
(Chemical Equation Presented) β-Aryl-β-ketophosphonates can be efficiently prepared in good yield by using a TFAA/85% H3PO 4-mediated acylation of electron-rich arenes with phosphonoacetic acids. The conditions offer advantages over
