858674-01-8Relevant academic research and scientific papers
Compounds with medicinal effects due to interaction with the glucocorticoid receptor
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Page/Page column 8, (2010/11/27)
The invention provides for compounds having the structure according to the formula I
Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity
Galiano, Silvia,Ceras, Javier,Cirauqui, Nuria,Perez, Silvia,Juanenea, Laura,Rivera, Gildardo,Aldana, Ignacio,Monge, Antonio
, p. 3896 - 3911 (2008/02/11)
We have designed and synthesized two novel series of MCH-R1 antagonists based on a substituted biphenylmethyl urea core. SAR was explored, suggesting that optimal binding with the receptor was achieved when the biphenylmethyl group and the linker were sub
