858679-43-3

Basic information

• Product Name: 2-Propynoic acid, 3-[2-chloro-4-(trifluoromethyl)phenyl]-, ethyl ester
• CAS NO: 858679-43-3
• Molecular Formula: C12H8ClF3O2
• Molecular Weight: 276.643
• Mol File: 858679-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propynoic acid, 3-[2-chloro-4-(trifluoromethyl)phenyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-[2-chloro-4-(trifluoromethyl)phenyl]-, ethyl ester(858679-43-3)
• EPA Substance Registry System: 2-Propynoic acid, 3-[2-chloro-4-(trifluoromethyl)phenyl]-, ethyl ester(858679-43-3)

Safety Data

• Hazardous Substances Data: 858679-43-3(Hazardous Substances Data)

Upstream product

• 141738-80-9 2-chloro-1-iodo-4-(trifluoromethyl)benzene 
• 623-47-2 propynoic acid ethyl ester 

Downstream Products

• 858678-49-6 (2-chloro-4-trifluoromethyl-phenyl)-propynoic acid 

Relevant articles and documents

3-(4-PIPERIDINE-1YLMETHYL-PHENYL)-PROPION ACID-PHENYLAMIDE-DERIVATIVES AND RELATED COMPOUNDS USED IN THE FORM OF MCH ANTAGONISTS (MELANINE CONCENTRATING HORMONE) FOR TREATING EATING DISORDERS

The invention relates to amid compounds of general formula (I), wherein groups and residuals A, B, b, W, X, Y, Z, R1, R2 and R3 have significances given in a claim 1. In addition, said invention relates to drugs containing at least one type of inventive amid. Because of the antagonist activity of an MCH-receptor, the inventive drugs are suitable for treating metabolic disturbances and/or eating disorders, in particular adiposity, bulimia, anorexia, hyperphagia and diabetes.