85871-32-5Relevant academic research and scientific papers
Ester of 1,1-dioxopenicillanic acid, and use thereof as β-lactamase inhibitor
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, (2008/06/13)
A 1,1-dioxopenicillanic acid ester represented by formula (I) STR1 wherein R represents a methyl or phenyl group. The ester of formula (I) may be prepared by reacting 1,1-dioxopenicillanic acid or its salt with a compound represented by formula (III) STR2 wherein R is as defined above, and X represents a halogen atom, or by oxidizing a compound of formula (V) STR3 wherein R is as defined above. The ester of the formula (I) is useful as a β-lactamase inhibitor and may be used in association with a β-lactam antibiotic.
