85873-09-2

Basic information

• Product Name: Sodium; (S)-4-hydroxy-hexanoate
• CAS NO: 85873-09-2
• Molecular Weight: 154.141
• Mol File: 85873-09-2.mol

Chemical Properties

• CAS DataBase Reference: Sodium; (S)-4-hydroxy-hexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium; (S)-4-hydroxy-hexanoate(85873-09-2)
• EPA Substance Registry System: Sodium; (S)-4-hydroxy-hexanoate(85873-09-2)

Safety Data

• Hazardous Substances Data: 85873-09-2(Hazardous Substances Data)

Upstream product

• 695-06-7 hexan-4-olide 
• 101853-52-5 (S)-4-Hydroxy-hexanoic acid methyl ester 
• 101853-50-3 (S)-4-Hydroxy-hexanoic acid ethyl ester 

Downstream Products

• 1117-74-4 4-oxohexanoic acid 

Relevant articles and documents

A simple oxidation of γ- and δ-lactones to oxocarboxylic acids by buffered sodium hypochlorite

An efficient synthetic procedure is described for the preparation of 4- and 5-oxocarboxylic acids by reaction of the corresponding lactones with commercial bleach.

Catalytic Asymmetric Synthesis of Alkyl Substituted Lactones by Enantioselective and Chemoselective Alkylation of Formylesters with Dialkylzincs Using N,N-Dibutylnorephedrine

Optically active 4-alkyl-γ-butyrolactones and 5-alkyl-6-valerolactones were obtained in high enantiomeric excesses (85-95percent e.e.) from the catalytic asymmetric alkylation of 3- and 4-formylesters with dialkylzincs using N,N-dibutylnorephedrine as catalyst.

KINETIC RESOLUTION OF LACTONES BY ENANTIOSELECTIVE PROTONATION OF THE CORRESPONDING CARBOXYLATE WITH A CHIRAL ACID

Racemic lactones were optically activated through the hydrolysis with sodium hydroxide followed by the partial neutralisation with (1S)-(+)-10-camphorsulfonic acid in ethanol to afford R- or S-isomer with 99 - 38percent ee.