85890-67-1Relevant articles and documents
Continuous Flow Liquid-Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N -Bromosuccinimide
O'Brien, Matthew,Cooper, Dennis
, p. 164 - 168 (2016)
Incorporating open-source software components (Python, OpenCV), a computer-vision system was used to control the interface level in a gravity-based inline liquid-liquid separation device. This was used in the continuous flow bromination of a series of enaminone substrates. The main byproduct of the reaction, succinimide, was efficiently extracted into the aqueous stream, providing clean products without the need for further purification.
Continuous flow iodination using an automated computer-vision controlled liquid-liquid extraction system
O'Brien, Matthew,Cooper, Dennis A.,Dolan, Jonathan
, p. 829 - 834 (2017/02/10)
A dynamic computer-vision control system incorporating open-source software technologies (Python, OpenCV) was used to automate a gravity based in-line liquid-liquid extraction during the iodination of enaminones in continuous flow. The system was able to cope with significant colouration of the organic reaction stream and with significant volume/flow changes in the aqueous and organic phase streams due to extraction of the water soluble acetonitrile co-solvent.