85893-44-3

Upstream product

• 85893-35-2 N-(1-Methyl-1-oxy-piperidin-4-yl)-N-phenyl-propionamide 
• 85893-41-0 trans-(+/-)-N-(2-Cyano-1-methyl-4-piperidyl)-N-phenylpropanamide 

Downstream Products

• 85221-34-7 (2R,4R)-1-Methyl-4-(phenyl-propionyl-amino)-piperidine-2-carboxylic acid benzylamide 
• 85221-48-3 trans-(+/-)-1-methyl-4-(N-phenylpropanamido)-piperidine-2-carboxylic acid hydrochloride 
• 85908-76-5 cis-(+/-)-1-Methyl-4-(N-phenylpropanamido)-piperidine-2-carboxamide 

Relevant academic research and scientific papers

Stereochemistry of Cyanide Ion Addition to 3,4,5,6-Tetrahydropyridinium Derivatives

The stereochemistry of cyanide ion addition to 1-alkyl-4-(N-phenylpropanamido)-3,4,5,6-tetrahydropyridinium salts 2 was investigated by analysis of the 1H NMR spectra of the isolated α-amino nitriles.The data obtained, together with epimerization studies, indicated that the addition occurred in a stereospecific manner to afford the trans diastereoisomeres.