858972-93-7Relevant academic research and scientific papers
Synthesis of the key precursor of Hirsutellide A
Xu, Yanjie,Duan, Xuemin,Li, Meiling,Jiang, Liqin,Zhao, Guangle,Meng, Yi,Chen, Ligong
, p. 259 - 264 (2005)
Hexadepsipeptide 2, the precursor of Hirsutellide A (1), was synthesized in an overall yield of 45% from N-Boc-Me-Gly via three coupling reactions using dicyclohexylcarbodiimide (DCC), O-(7-azabenzotriazol-1-yl)-N,N,N′, N′-tetramethyluronium hexafluorophosphate (HATU) and bis(2-oxo-3- oxazolidinyl)phosphinic chloride (BOP-Cl), respectively.
