85902-43-8Relevant academic research and scientific papers
Copper(ii) and zinc(ii) complexes of mono- And bis-1,2,3-triazole-substituted heterocyclic ligands
Kirin, Sre?ko I.,Krklec, Marko,Novosel, Tiana,Pantalon Juraj, Natalija,Peri?, Berislav,Rai?-Mali?, Silvana,Vianello, Robert
, p. 9002 - 9015 (2020/07/15)
Chelating 1,4-disubstituted mono- (8a-8d) and bis-1,2,3-triazole-based (9a-11a) ligands were prepared by regioselective copper(i)-catalysed 1,3-dipolar cycloaddition of terminal alkynes with aromatic azides, together with bioconjugate 13a synthesized by amide coupling of l-phenylalanine methyl ester to 11a. Cu(ii) and Zn(ii) complexes were prepared and single crystal structures were determined for complexes 8aCu, 8dCu, 9cCu and 10cCu, as well as the free ligands 10a and 10c. The in situ prepared Zn(ii) complexes were studied by NMR spectroscopy, while the stoichiometry of the Cu(ii) complexes in solution was determined by UV-Vis titrations and confirmed by the electronic structure DFT calculations at the (SMD)/M05-2X/6-31+G(d)/LanL2DZ+ECP level of theory.
Silver-catalyzed intramolecular hydroamination of alkynes in aqueous media: Efficient and regioselective synthesis for fused benzimidazoles
Zhang, Xu,Zhou, Yu,Wang, Hengshuai,Guo, Diliang,Ye, Deju,Xu, Yungen,Jiang, Hualiang,Liu, Hong
supporting information; experimental part, p. 397 - 405 (2011/04/17)
A simple, convenient and green synthetic approach to diverse fused tricyclic benzimidazoles has been developed by Ag(i) complex catalyzed intramolecular hydroamination under the classic method or by microwave irradiation in water. This strategy presents a
An effective synthetic entry to fused benzimidazoles via iodocyclization
Zhang, Xu,Zhou, Yu,Wang, Hengshuai,Guo, Diliang,Ye, Deju,Xu, Yungen,Jiang, Hualiang,Liu, Hong
supporting information; experimental part, p. 1429 - 1437 (2011/08/03)
A protocol for the synthesis of the fused heterocyclic polycyclic compounds pyrrole[1,2-a]benzimidazoles, piperidine[1,2-a]benzimidazoles and oxa-fused benzimidazoles using iodine and silver nitrate by an exo-dig or endo-dig cyclization pathway at room te
Facile rearrangements of alkynylamino heterocycles with noble metal cations
Lok, Roger,Leone, Ronald E.,Williams, Antony J.
, p. 3289 - 3297 (2007/10/03)
A number of 2-(alkynylamino)-substituted heterocycles have been synthesized. These heterocycles rearrange in the presence of silver(I) and gold(I) salts to give novel 2H-pyrimido[2,1-b]benzoxazoles, 2H-pyrimido[2,1-b]benzothiazoles, and a 2H-pyrimido[2,1-b]benzoselenazole. Two of the the 2H-pyrimido[2,1-b]benzoxazoles were isolated in good yield. The kinetics of the silver tetrafluoroborate-catalyzed rearrangements of selected (alkynylamino)benzoxazoles and benzothiazoles have been examined by 1H NMR in CD3CN. Factors affecting the electron densities of the triple bond and of the nitrogen atom in the heterocycle are important in influencing the rate of rearrangement.
Propynylaminothiazole derivatives
-
, (2008/06/13)
New 2-(2-propynylamino)thiazole and 2-(3-iodo-2-propynylamino)thiazole derivatives having anti-microbial activity which are used as an active ingredient in anti-microbial compositions for medical and agricultural use.
