85920-95-2Relevant academic research and scientific papers
A REGIOSPECIFIC SYNTHESIS OF γ-KETO ESTERS: THE ALKYLATION OF O-SILYLATED ENOLATES WITH METHYL α-CHLORO-α-PHENYLTHIOACETATE
Lee, Thomas V.,Okonkwo, Jonathan O.
, p. 323 - 326 (2007/10/02)
Methyl α-chloro-α-phenylthio acetate (2) regiospecifically alkylates O-silylated enolates to form γ-keto esters.
THE METHOXYCARBONYLALKYLATION AND METHOXYCARBONYLALKYLIDENATION OF SILYL ENOL ETHERS
Fleming, Ian,Iqbal, Javed
, p. 327 - 328 (2007/10/02)
Silyl enol ethers (1) react with the phenylthio(methoxycarbonyl)alkyl chlorides (2) in the presence of Lewis acids to give good yields of the γ-ketoesters (3); oxidative and reductive desulphurisations give the saturated (4) and unsaturated (5 or 6) γ-ket
