859213-33-5

Basic information

• Product Name: (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate
• CAS NO: 859213-33-5
• Molecular Weight: 230.307
• Mol File: 859213-33-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate(859213-33-5)
• EPA Substance Registry System: (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate(859213-33-5)

Safety Data

• Hazardous Substances Data: 859213-33-5(Hazardous Substances Data)

Usage

General Description

The chemical (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate is a compound with a molecular formula C12H24N2O3. It belongs to the class of pyrrolidine carboxylates and is a derivative of pyrrolidine. This chemical is made up of a tert-butyl group, a dimethylamino group, and a hydroxyl group attached to the pyrrolidine ring. It is commonly used in organic synthesis and pharmaceutical research due to its potential as a building block in creating new compounds with therapeutic properties. (3S,4S)-tert-butyl 3-(dimethyl amino)-4-hydroxypyrrolidine-1-carboxylate may have applications in drug development and the creation of new biological molecules.

Upstream product

• 50-00-0 formaldehyd 
• 190792-74-6 (3S,4S)-4-amino-1-N-tert-butyloxycarbonyl-3-hydroxypyrrolidine 
• 252574-03-1 (3S,4S)-1-tert-butoxycarbonyl-trans-3-benzylamino-4-hydroxypyrrolidine 

Downstream Products

• 960289-61-6 (3S,4S)-4-(dimethylamino)pyrrolidin-3-ol 

Relevant articles and documents

QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS

The present application relates to novel quinazoline compounds as inhibitors of type I receptor tyrosine kinases, the pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and the use of the compounds and salts thereof in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals and especially in humans.

AMIDE DERIVATIVE AND MEDICINE

The present invention is directed to an amide derivative having excellent BCR-ABL tyrosine kinase inhibitory activity, or a salt thereof. The present invention provides an amide derivative represented by the following general formula [1]: (wherein R1 represents -CH2-R11, etc.; R2 represents alkyl, halogen, haloalkyl, etc.; R3 represents hydrogen, etc.; Het1 represents a group of the formula [6] as above, etc.; and Het2 represents pyrimidinyl, etc.), or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient. The compound of the present invention is useful as a BCR-ABL tyrosine kinase inhibitor.