859502-08-2Relevant academic research and scientific papers
Synthesis of azamacrocycles via a Mitsunobu reaction
Hovinen, Jari,Sillanp??, Reijo
, p. 4387 - 4389 (2005)
Reaction of pernosylated diethylenetriamine and 2-substituted propane-1,3-diols in dry THF in the presence of triphenylphosphine and diisopropyl azodicarboxylate gives the corresponding protected 9-substituted 1,4,7-triazacyclodecanes. The Mitsunobu reaction was also used in the preparation of 3-substituted 1,5,9-triazacyclododecanes and macrocyclic pyridine derivatives.
