85972-04-9Relevant academic research and scientific papers
Synthesis of 2-aminoquinoxalines via one-pot cyanide-based sequential reaction under aerobic oxidation conditions
Cho, Yeon-Ho,Kim, Kyung-Hee,Cheon, Cheol-Hong
, p. 901 - 907 (2014/03/21)
A highly efficient synthesis of 2-aminoquinoxalines has been developed via the one-pot two-step cyanide-mediated sequential reactions of ortho-phenylenediamines with aldehydes under aerobic oxidation conditions. A variety of substrates, including aliphati
An efficient and environmental benign synthesis of 2-benzimidazoles and 2-benzothiazoles using CeCl3-NaI as catalyst
Zhu, Xun,Wei, Yunyang
, p. 119 - 121 (2013/04/23)
A one-pot condensation of an aldehyde with 1,2-phenylenediamine or 2-aminothiophenol in dimethyl carbonate at 100°C under O2 in the presence of catalytic amounts of CeCl3-NaI gave an imine intermediate, which cyclised and dehydrogenated to give 2-arylbenzimidazoles or 2-arylbenzothiazoles in good yields.
Ni nanoparticles: Mild and efficient catalyst for the chemoselective synthesis of 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines
Khurana, Jitender M.,Sneha,Vij, Kanika
experimental part, p. 2606 - 2616 (2012/08/08)
(Chemical Equation Presented) A new and efficient method has been developed for the synthesis of biologically significant 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines using recyclable and inexpensive polyvinyl pyrrolidone (PVP)-stabilized Ni nanoparticles in ethylene glycol at room temperature in excellent yields. Copyright Taylor & Francis Group, LLC.
Novel method for the syntheses of 2-substituted benzimidazoles using Ti(IV) isopropoxide and cumene hydroperoxide
Havaldar, Freddy H.,Mule, Ganesh,Dabholkar, Bhushan
experimental part, p. 2304 - 2308 (2011/06/27)
Various 2-substituted benzimidazoles were prepared in one pot by condensation of o-phenylenediamine with an appropriate aldehyde in good to excellent yields using a mixture of Ti(IV) isopropoxide and cumene hydroperoxide. Copyright
Water-mediated synthesis of 2-substituted benzimidazoles by boric acid and glycerol
Mukhopadhyay, Chhanda,Tapaswi, Pradip Kumar,Butcher, Ray J.
experimental part, p. 140 - 144 (2009/08/15)
A very simple, mild, and highly efficient green catalyst has been developed for the synthesis of 2-substituted benzimidazoles by treatment of substituted ortho-phenylenediamines and aldehydes in water at 80C in the presence of boric acid (5 mol-%) and glycerol (0.05 mL). This methodology has been standardized on 55 substrates, and nine new compounds have been synthesized.
Investigation of the products of interaction of cyclic diketones with nitrogen-containing 1,4-binucleophiles
Kolos,Yurchenko,Orlov,Shishkina,Shishkin
, p. 1550 - 1559 (2007/10/03)
The interaction of arylbis(5,5-dimethylcyclohexane-1,3-dion-2-yl)methanes with o-phenylenediamine and o-aminophenol leads to the preparation of 3,3-dimethyl-11-aryl-2,3,4,5,10,11-hexahydrobenzo[b,e]-1,4-diazepin-1-ones and 3,3,6,6-tetramethyl-9-aryl-10-(2
Intermediates in the reaction of o-phenylenediamine with carbonyl compounds and their subsequent conversions
Zelenin,Ukraintsev,Alekseev
, p. 329 - 333 (2007/10/03)
The reaction of o-phenylenediamine with aldehydes and ketones has been studied using PMR spectroscopy. It has been established that the reaction begins with the formation of monoimines (isolated in condensations with aromatic aldehydes) which are cyclized
Studies about the cyclization of 1,2-diamines with aldehydes and ketones
Lessel
, p. 649 - 653 (2007/10/02)
The reaction of the 1,2-dinucleophile ethylendiamine with benzaldehydes yields diimines, from o-phenylendiamine monoimines respectively benzimidazoles are formed. β-Diketones give 1,5-benzodiazepines. The different behaviour is explained by MNDO calculati
