859831-52-0

Upstream product

• 52602-39-8 9H-carbazol-4-ol 
• 100-39-0 benzyl bromide 
• 142505-59-7 2'-benzyloxy-2-nitrobiphenyl 

Downstream Products

• 859831-65-5 4-(2-(4-benzyloxycarbazol-9-yl)ethoxy)benzaldehyde 
• 890017-27-3 4-benzyloxy-9-(2-methoxy-ethyl)-9H-carbazole 
• 859831-75-7 ethyl 2-ethoxy-3-{4-[2-(4-benzyloxycarbazol-9-yl)ethoxy]phenyl}propionate 
• 859831-70-2 ethyl 2-ethoxy-3-{4-[2-(4-benzyloxycarbazol-9-yl)ethoxy]phenyl}-2-propenoate 
• 859831-74-6 ethyl 2-ethoxy-3-{4-[2-(4-hydroxycarbazol-9-yl)ethoxy]phenyl}propionate 

Relevant academic research and scientific papers

Macroscopic Wires from Fluorophore-Quencher Dyads with Long-Lived Blue Emission

We report the formation of macroscopic wires up to centimeters in length from a series of structurally flexible, covalently tethered small-molecular fluorophore-quencher dyads (FQDs, average MW = 425 Da), comprised of carbazole, melatonin, and cyanobenzoa

Suzuki-Miyaura cross-coupling of 2-nitroarenediazonium tetrafluoroborates: Synthesis of unsymmetrical 2-nitrobiphenyls and highly functionalized carbazoles

The Suzuki-Miyaura cross-coupling of 2-nitrodiazonium tetrafluoroborate salts with substituted boronic acids is an effective and efficient means of preparing highly functionalized 2-nitrobiphenyls in modest to excellent yield under extremely mild reaction conditions. Cross-coupling of 2-nitrodiazonium tetrafluoroborate salts with ortho-methoxy- and benzyloxyphenylboronic acids was also demonstrated leading to the ortho-ortho-2-nitrobiphenyls. Reductive cyclization of the 2-nitrobiphenyl products allows for the overall three-step synthesis of uniquely substituted carbazoles from readily available 2-nitroanilines. The methodology was further highlighted by the short total synthesis of the carbazole alkaloids clausine V, N, C, and glycoborine.

CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE

The present invention provides compounds possessing inhibitory activity against ? adrenergic receptors and phosphodiesterase (PDE), including type 3 phosphodiesterase (PDE-3). The present invention further provides pharmaceutical compositions comprising s

Design, synthesis and evaluation of carbazole derivatives as PPARα/γ dual agonists and antioxidants

A series of hydroxycarbazole derivatives were synthesized and evaluated for PPARα/γ dual agonist as well as antioxidant activities. While most compounds showed good antioxidant activity, some compounds were identified as potential PPARα/γ dual agonists as well. Compounds 10a and 16 were found to be active in animal studies.