859831-71-3Relevant articles and documents
Design, synthesis and evaluation of carbazole derivatives as PPARα/γ dual agonists and antioxidants
Kumar, Rakesh,Ramachandran, Uma,Srinivasan, Krishnamoorthy,Ramarao, Poduri,Raichur, Suryaprakash,Chakrabarti, Ranjan
, p. 4279 - 4290 (2007/10/03)
A series of hydroxycarbazole derivatives were synthesized and evaluated for PPARα/γ dual agonist as well as antioxidant activities. While most compounds showed good antioxidant activity, some compounds were identified as potential PPARα/γ dual agonists as well. Compounds 10a and 16 were found to be active in animal studies.