859849-56-2Relevant academic research and scientific papers
Microwave-assisted flexible synthesis of 7-azaindoles
Schirok, Hartmut
, p. 5538 - 5545 (2007/10/03)
7-Azaindoles are versatile building blocks, especially in medicinal chemistry, where they serve as bioisosteres of indoles or purines. Herein, we are presenting a robust and flexible synthesis of 1,3- and 1,3,6-substituted 7-azaindoles starting from nicot
A versatile synthesis of 7-azaindoles
Schirok, Hartmut
, p. 1255 - 1258 (2007/10/03)
1,3-Disubstituted 7-azaindoles were synthesized from 2,6-dichloropyridine using DoM and intramolecular aromatic substitution after epoxide opening by an amine. Even the sterically demanding adamantylamine may be incorporated leading to derivatives which a
