859877-49-9

Upstream product

• 16554-45-3 2-methoxy-6-nitroaniline 
• 924274-94-2 2-amino-5-chloro-3-nitrophenol 
• 74-88-4 methyl iodide 
• 603-85-0 2-Amino-3-nitrophenol 

Downstream Products

• 55910-07-1 1-chloro-3-methoxy-5-nitrobenzene 
• 859877-50-2 4-chloro-2-methoxy-N-methyl-6-nitroaniline 
• 1255789-24-2 5-chloro-3-methoxybenzene-1,2-diamine 

Relevant academic research and scientific papers

COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS

The disclosure provides compounds and pharmaceutical compositions of the compounds useful for treating chronic and acute bacterial infections. Certain of the compounds are compounds and salts of general Formula VIII Certain compounds of this disclosure are MvfR inhibitors. MvfR inhibitors reduce the formation of antibiotic tolerant bacterial strains and are useful for treating Gram-negative bacterial infections and reducing the virulence of Pseudomonas aeruginosa. Methods of treating bacterial infections in a patient, including Pseudomonas aeruginosa infections, are also provided by the disclosure.

Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists

The present invention relates to urotensin II receptor antagonists, pharmaceutical compositions containing them and their use.

CYCLIC GUANIDINES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

The present invention relates to cyclic guanidines, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.