859942-25-9

Upstream product

• 54370-01-3 1-bromo-2-(chloromethyl)-4,5-dimethoxy-benzene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 5963-51-9 1,2-bis(3,4-dimethoxyphenyl)ethane 
• 5385-62-6 3,3’,4,4’-tetramethoxystilbene 
• 554-34-7 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione 
• 18513-98-9 3,4,3',4'-Tetramethoxystilben 
• 2859-78-1 4-Bromoveratrole 

Downstream Products

• 5963-51-9 1,2-bis(3,4-dimethoxyphenyl)ethane 

Relevant academic research and scientific papers

Total synthesis of the marine metabolite (±)-Polysiphenol via highly regioselective intramolecular oxidative coupling

(±)-Polysiphenol (1), an atropisomerically stable 4,5-dibrominated 9,10-dihydrophenanthrene from Polysiphonia ferulacea, was prepared by a biomimetically inspired highly regioselective intramolecular oxidative coupling of a dibrominated dihydrostilbene. T

Selective Preparation of Polycyclic Aromatic Hydrocarbons. Part 7. A Preparative Route to 10,11-Dihydro-5H-dibenzo-cycloheptenes Using Friedel-Crafts Intramolecular Cyclobenzylation

Cyclobenzylation of 2-hydroxymethyldiphenylethanes 4 and 2,2'-bis(hydroxymethyl)diphenylethanes 13 in the presence of a solid perfluorinated sulfonic acid resin, Nafion-H, as a catalyst results in novel polycyclic aromatic hydrocarbons, dibenzocyclopentenes.Dibenzocyclopentenes were also prepared from diphenylethanes by a benzylation reaction, which incorporates chloromethylation of a hydrocarbon followed by Friedel-Crafts intramolecular cyclization reaction.The present method involving the action of ClCH2OMe and TiCl4 on a variety of diphenylethanes (constructed such that electrophilic substitution occurs ortho to the diphenylethane linkage) offers a convenient, mild one-pot synthesis of substituted dibenzocycloheptenes.The mechanism of these reactions is also discussed.