859965-07-4

Upstream product

• 1355659-10-7 N-methyl-1-(1-methyl-2-phenyl-1H-indol-3-yl)methanamine 
• 3558-24-5 1-methyl-2-phenyl-1H-indole 
• 1757-72-8 1-methyl-2-phenyl-1H-indole-3-carbaldehyde 
• 1364521-86-7 N-methyl-N-(2-(phenylethynyl)phenyl)formamide 

Downstream Products

• 938305-58-9 (1-methyl-2-phenyl-1H-indol-3-yl)methanamine 
• 1354817-33-6 N-((1-methyl-2-phenyl-1H-indol-3-yl)methyl)formamide 
• 1757-72-8 1-methyl-2-phenyl-1H-indole-3-carbaldehyde 
• 87613-34-1 1-methyl-2-phenyl-1H-indole-3-carbonitrile 

Relevant academic research and scientific papers

Ruthenium-catalyzed annulation of alkynes with amides via formyl translocation

The first example of Ru-catalyzed intramolecular annulation of alkynes with amides via formyl translocation has been developed, which provides an efficient approach for the synthesis of 1H-indole-3-carbaldehydes. The Royal Society of Chemistry 2012.

Direct transformation of N, N -dimethylformamide to -CN: Pd-catalyzed cyanation of heteroarenes via C-H functionalization

This paper describes the direct cyanation of indoles and benzofurans employing N,N-dimethylformamide (DMF) as both reagent and solvent. Isotopic labeling experiments indicated that both the N and the C of the cyano group derived from DMF. This transformation offers an alternative method for preparing aryl nitriles, though it is currently limited in scope to indoles and benzofurans.