1757-72-8Relevant articles and documents
Cu/Fe-cocatalyzed meyer-schuster-like rearrangement of propargylic amines: Direct access to e -β-aminoacryaldehydes
Chen, Ming,Peng, Jiangling,Mao, Tingting,Huang, Jinbo
, p. 6286 - 6289 (2014)
A simple and efficient method for the synthesis of β-aminoacryaldehydes via Cu(OAc)2·H2O and FeCl3 cocatalyzed Meyer-Schuster-Like rearrangement of propargylic amines was developed. The reactions proceed selectively as the E-isomers in generally good yields under aerobic conditions, and are compatible with a broad range of functional groups. This method combines C-N bond cleavage as well as the N-aryl group migration and provides a practical and mild synthetic approach to α,β-unsaturated carbonyl compounds, which are useful precursors in a variety of functional group transformations.
Synthesis and application of cyanoacrylate ultraviolet blue light absorbent
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Paragraph 0027-0032; 0036-0040, (2021/06/13)
The invention discloses synthesis and application of a cyanoacrylate ultraviolet blue light absorbent, and belongs to the technical field of organic functional materials. The preparation method comprises the following steps: 1, mixing N-substituted formamide and a catalyst, conducting reacting to prepare a Vilsmeier-Haack reagent, slowly adding materials, and controlling the internal temperature of a system to be 25-60 DEG C; 2, carrying out a reaction on an indole derivative (M1) and a Vilsmeier-Haack reagent, and treating the reaction liquid with an alkali to prepare a compound M2; and 3, carrying out homogeneous reaction on the compound M2 and cyanoacetate under the action of a catalyst to prepare a compound M3. The cyanoacrylate indole derivative compound prepared by the invention is a novel ultraviolet blue light absorbent, has the excellent characteristics of high absorption efficiency, wide protection wave band, strong selective permeability and almost no absorption of visible light, and has wide application space in the field of high polymer material protection, especially in the field of optical functional materials, meanwhile, synthesis raw materials are cheap and easy to obtain, and the synthesis process is high in operability.
Access to Polycyclic Sulfonyl Indolines via Fe(II)-Catalyzed or UV-Driven Formal [2 + 2 + 1] Cyclization Reactions of N-((1H-indol-3-yl)methyl)propiolamides with NaHSO3
Lu, Lin,Luo, Chenguang,Peng, Hui,Jiang, Huanfeng,Lei, Ming,Yin, Biaolin
supporting information, p. 2602 - 2605 (2019/04/30)
A variety of structurally novel polycyclic sulfonyl indolines have been synthesized via FeCl2-catalyzed or UV-driven intramolecular formal [2 + 2 + 1] dearomatizing cyclization reactions of N-(1H-indol-3-yl)methyl)propiolamides with NaHSO3 in an aqueous medium. The reactions involve the formation of one C-C bond and two C-S bonds in a single step.
