860011-18-3

Upstream product

• 79-01-6 Trichloroethylene 
• 102225-88-7 (-)-(S)-1-(2,4,6-triisopropylphenyl)ethanol 

Downstream Products

• 860011-19-4 2-((S)-1-Hept-6-en-1-ynyloxy-ethyl)-1,3,5-triisopropyl-benzene 
• 1240520-79-9 (S)-O-vinyl-1-(2,4,6-triisopropylphenyl)ethanol 
• 1611460-90-2 1,2-dimethyl 3-[(S)-1-(2,4,6-triisopropylphenyl)ethyl] (R)-2-(2,2,2-trifluoroacetamido)propane-1,2,3-tricarboxylate 
• 1611460-89-9 methyl (3S,5R)-3-(2-methoxy-2-oxoethyl)-2-(2,2,2-trifluoroacetyl)-5-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]isoxazolidine-3-carboxylate 
• 1611460-84-4 methyl (3S,5R)-3-(2-methoxy-2-oxoethyl)-5-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]isoxazolidine-3-carboxylate 
• 1611460-77-5 methyl (3R,5S)-2-benzhydryl-3-(2-methoxy-2-oxoethyl)-5-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]isoxazolidine-3-carboxylate 
• 1611460-75-3 methyl (3R,5S)-2-benzyl-3-(2-methoxy-2-oxoethyl)-5-[(S)-1-(2,4,6-triisopropylphenyl)ethoxy]isoxazolidine-3-carboxylate 
• 165054-17-1 (-)-2-((1S)-1-((1E)-1-propenyloxy)ethyl)-1,3,5-triisopropylbenzene 
• 860011-21-8 (3S,4R)-2,2-Dichloro-4-pent-4-enyl-3-[(S)-1-(2,4,6-triisopropyl-phenyl)-ethoxy]-cyclobutanone 
• 860011-20-7 2-{(S)-1-[((Z)-Hepta-1,6-dienyl)oxy]-ethyl}-1,3,5-triisopropyl-benzene 

Relevant academic research and scientific papers

Asymmetric access to α-substituted functional aspartic acid derivatives by a [3+2] strategy employing a chiral dienophile

Enantiopure vinyl ethers of Stericol underwent diastereoselective thermal 1,3 dipolar cycloadditions with N-benzyl, N-benzhydryl, and N-PMB aspartate ester nitrones. Chemoselective N-debenzylation of the resulting cycloadducts afforded diastereomerically and enantiomerically pure crystalline NH-isoxazolidine, the absolute configuration of which was established by X-ray crystallography. N-Protection and N-O cleavage of this isoxazolidine gave enantioenriched quaternary aspartate derivatives bearing functionalized side chains.

Formal synthesis of (+)-anatoxin-a by asymmetric [2+2] cycloaddition

A formal asymmetric synthesis of (+)-anatoxin-a, a neurotoxic alkaloid from Anabaena flos aquae, has been achieved through a highly diastereoselective [2+2] cycloaddition of dichloroketene with a chiral enol ether.