860232-96-8 Usage
Uses
Used in Pharmaceutical Industry:
3-Quinolinol, 6-chlorois used as a building block for the synthesis of pharmaceuticals due to its ability to form a wide range of chemical structures. Its unique properties allow it to be incorporated into various drug molecules, potentially enhancing their therapeutic effects and pharmacological profiles.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Quinolinol, 6-chlorois utilized as a precursor in the development of new agrochemicals. Its chemical structure can be modified to create compounds with pesticidal or herbicidal properties, contributing to more effective crop protection strategies.
Used in Dye Industry:
3-Quinolinol, 6-chlorois employed as a building block in the synthesis of dyes due to its ability to impart color to various substrates. Its chemical versatility allows for the creation of dyes with different shades and properties, suitable for various applications in textiles, plastics, and other industries.
Used in Analytical Chemistry:
3-Quinolinol, 6-chlorois used as a chelating agent in analytical chemistry. Its ability to form stable complexes with metal ions makes it a valuable tool in the detection, separation, and quantification of various metal species in samples.
Used in Organic Reactions:
As a catalyst, 3-Quinolinol, 6-chlorois employed in various organic reactions to enhance their efficiency and selectivity. Its unique chemical properties can facilitate specific reaction pathways, leading to improved yields and more favorable product distributions.
Used in Antibacterial and Antifungal Applications:
3-Quinolinol, 6-chlorohas been studied for its potential antibacterial and antifungal properties. Its ability to inhibit the growth of certain bacteria and fungi makes it a promising candidate for the development of new antimicrobial agents to combat drug-resistant infections.
Used in Anticancer Research:
3-Quinolinol, 6-chlorohas also been investigated for its potential to inhibit the growth of certain cancer cells. Its ability to interfere with specific cellular processes may contribute to the development of novel anticancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 860232-96-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,2,3 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 860232-96:
(8*8)+(7*6)+(6*0)+(5*2)+(4*3)+(3*2)+(2*9)+(1*6)=158
158 % 10 = 8
So 860232-96-8 is a valid CAS Registry Number.
860232-96-8Relevant academic research and scientific papers
Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB 2) agonists
Cheng, Yuan,Albrecht, Brian K.,Brown, James,Buchanan, John L.,Buckner, William H.,DiMauro, Erin F.,Emkey, Renee,Fremeau Jr., Robert T.,Harmange, Jean-Christophe,Hoffman, Beth J.,Huang, Liyue,Huang, Ming,Lee, Josie Han,Lin, Fen-Fen,Martin, Matthew W.,Nguyen, Hung Q.,Patel, Vinod F.,Tomlinson, Susan A.,White, Ryan D.,Xia, Xiaoyang,Hitchcock, Stephen A.
experimental part, p. 5019 - 5034 (2009/07/19)
The CB2 receptor is an attractive therapeutic target for analgesic and anti-inflammatory agents. Herein we describe the discovery of a novel class of oxadiazole derivatives from which potent and selective CB 2 agonist leads were developed. Initial hit 7 was identified from a cannabinoid target-biased library generated by virtual screening of sample collections using a pharmacophore model in combination with a series of physicochemical filters. 7 was demonstrated to be a selective CB2 agonist (CB2 EC50 = 93 nM, Emax = 98%, CB 1 EC50 > 10 μM). However, this compound exhibited poor solubility and relatively high clearance in rat, resulting in low oral bioavailability. In this paper, we report detailed SAR studies on 7 en route toward improving potency, physicochemical properties, and solubility. This effort resulted in identification of 63 that is a potent and selective agonist at CB2 (EC50 = 2 nM, Emax = 110%) with excellent pharmacokinetic properties.
