86031-03-0

Basic information

• Product Name: tert-Butyl-((2S,4R,6R)-2-iodomethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-diphenyl-silane
• Synonyms: tert-Butyl-((2S,4R,6R)-2-iodomethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-diphenyl-silane
• CAS NO: 86031-03-0
• Molecular Weight: 510.487
• Mol File: 86031-03-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-Butyl-((2S,4R,6R)-2-iodomethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl-((2S,4R,6R)-2-iodomethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-diphenyl-silane(86031-03-0)
• EPA Substance Registry System: tert-Butyl-((2S,4R,6R)-2-iodomethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-diphenyl-silane(86031-03-0)

Safety Data

• Hazardous Substances Data: 86031-03-0(Hazardous Substances Data)

Upstream product

• 110772-23-1 [(2S,4R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-methanol 
• 110772-22-0 2(RS)-methoxy-4(R)-(tert-butyldiphenylsiloxy)-6(S)-<<(p-tolylsulfonyl)oxy>methyl>tetrahydropyran 
• 86030-94-6 methyl 3-O-(tert-butyldiphenylsilyl)-2,4-dideoxy-β-D-erythro-hexopyranoside 
• 86030-93-5 tert-Butyl-((2S,4R,6S)-2-methoxy-6-trityloxymethyl-tetrahydro-pyran-4-yloxy)-diphenyl-silane 
• 86030-92-4 methyl 2,4-dideoxy-6-O-(triphenylmethyl)-α-D-erythro-hexopyranoside 

Downstream Products

• 108712-55-6 (2S,4R,6R)-2-{(3R,4R)-2-Benzenesulfonyl-3-[(1R,6R)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl]-4-methyl-hex-5-enyl}-4-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran 
• 108712-55-6 (2S,4R,6R)-2-{(3S,4S)-2-Benzenesulfonyl-3-[(1S,6S)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl]-4-methyl-hex-5-enyl}-4-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran 
• 90344-14-2 C₄₄H₅₈O₅S₃Si 
• 136007-62-0 4(R)-(tert-butyldiphenylsiloxy)-6(S)-<<2,4-dichloro-6-cyclohexylidenefluoromethyl)phenoxy>methyl>tetrahydropyran-2-one 
• 136085-62-6 4(R)-(tert-butyldiphenylsiloxy)-6(S)-<<2,4-dimethyl-6-(cyclohexylhydroxymethyl)phenoxy>methyl>tetrahydropyran-2-one 
• 136007-84-6 4(R)-(tert-butyldiphenylsiloxy)-6(S)-<<2,4-dimethyl-6-(cyclohexylhydroxymethyl)phenoxy>methyl>tetrahydropyran-2-one 
• 136007-84-6 4(R)-(tert-butyldiphenylsiloxy)-6(S)-<<2,4-dimethyl-6-(cyclohexylhydroxymethyl)phenoxy>methyl>tetrahydropyran-2-one 
• 136007-83-5 (4R,6S)-4-(tert-Butyl-diphenyl-silanyloxy)-6-[2-(cyclohexyl-hydroxy-methyl)-4,6-dimethyl-phenoxymethyl]-tetrahydro-pyran-2-ol 
• 136006-71-8 4(R)-hydroxy-6(S)-<<2,4-dimethyl-6-methyl>phenoxy>methyl>tetrahydropyran-2-one 
• 136006-72-9 4(S)-hydroxy-6(S)-<<2,4-dimethyl-6-methyl>phenoxy>methyl>tetrahydropyran-2-one 
• 136006-73-0 N-{(S)-Cyclohexyl-[2-((2S,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-ylmethoxy)-3,5-dimethyl-phenyl]-methyl}-2,2-dimethyl-butyramide 
• 136006-74-1 N-{(R)-Cyclohexyl-[2-((2S,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-ylmethoxy)-3,5-dimethyl-phenyl]-methyl}-2,2-dimethyl-butyramide 
• 136006-57-0 Sodium; (3R,5S)-6-{2-[(S)-cyclohexyl-(2,2-dimethyl-butyrylamino)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate 
• 136006-58-1 Sodium; (3R,5S)-6-{2-[(R)-cyclohexyl-(2,2-dimethyl-butyrylamino)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate 

Relevant articles and documents

Synthesis and Biological activity of new HMG-CoA reductase inhibitors. 3.1,2 lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids

A group of 43 optically active sodium carboxylates (11a-qq and the corresponding lactones 4 were prepared from respective phenols 8 according to Schemes I-III. Phenols 8 were synthesized from commercially available compounds according to Schemes IV-IX. A

MEVINIC ACIDS AND ANALOGUES: PREPARATION OF A KEY CHIRAL INTERMEDIATE

The preparation of methyl 3-O-tert-butyldiphenylsilyl-2,4-dideoxy-β-D-erytrohexopyranoside, a key chiral intermediate for mevinic acids, and its elaboration into four mevinate analogues are described.