860438-13-7Relevant academic research and scientific papers
BENZENE DERIVATIVE
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Paragraph 0789-0790, (2021/10/30)
A compound represented by general formula (I) (in the formula, all symbols are as described in the description) or a salt thereof has a potent nerve-protecting and/or -repairing activity, and therefore can be used as a therapeutic agent for neuropathy (e.
Synthesis of C1-C20 and C21-C40 fragments of tetrafibricin
Gudipati, Venugopal,Curran, Dennis P.
scheme or table, p. 2254 - 2257 (2011/05/09)
Efficient syntheses of suitably functionalized top and bottom fragments of tetrafibricin are described. The bottom fragment is prepared by two consecutive Kocienski-Julia couplings, while the top fragment synthesis features a dithiane alkylation and a Hor
Synthesis of undecachlorosulfolipid A: Re-evaluation of the nominal structure
Nilewski, Christian,Deprez, Nicholas R.,Fessard, Thomas C.,Li, Dong Bo,Geisser, Roger W.,Carreira, Erick M.
supporting information; experimental part, p. 7940 - 7943 (2011/10/08)
Halo-giant: The title compound at the left in the scheme was constructed by the synthesis and coupling of two stereochemically challenging fragments. A comparison of the NMR data of the synthetic material and the natural product indicates that the configuration had been misassigned in the latter. PT=5-(1-phenyltetrazolyl).
Fluorous mixture synthesis of four stereoisomers of the C21-C40 fragment of tetrafibricin
Zhang, Kai,Curran, Dennis P.
supporting information; experimental part, p. 667 - 671 (2010/12/18)
Four stereoisomers of the C21-C40 fragment are synthesized in a single exercise with the aid of fluorous tagging to encode configurations at C37 and C33. After demixing and detagging, the isomers were found to have substantially identical 1H NM
The polyol domain of amphidinol 3. A stereoselective synthesis of the entire C(1)-C(30) sector
Paquette, Leo A.,Chang, Shuh-Kuen
, p. 3111 - 3114 (2007/10/03)
(Chemical Equation Presented) The richly oxygenated C(1)-C(30) polyol segment of amphidinol 3 has been synthesized in protected form. Incorporated in this long chain are 10 of the 25 stereogenic centers housed in the target. The asymmetric pathway that has been developed is based on the efficient union of three independently prepared subunits.
