86051-40-3Relevant academic research and scientific papers
Highly selective metal catalysts for intermolecular carbenoid insertion into primary C-H bonds and enantioselective C-C bond formation
Thu, Hung-Yat,Tong, Glenna So-Ming,Huang, Jie-Sheng,Chan, Sharon Lai-Fung,Deng, Qing-Hai,Che, Chi-Ming
supporting information; scheme or table, p. 9747 - 9751 (2009/05/30)
(Figure Presented) Primary C-H bond activation! A Rh complex of bis-pocket porphyrin I catalyzes carbenoid insertion into the C-H bonds of n-alkanes with a primary/secondary selectivity (per C-H bond) of up to 11.4:1 (see picture). Enantioselective secondary C-H bond functionalization catalyzed by a Rh complex of Halterman's chiral porphyrin features up to 93% ee. These reactions exhibit up to 6477 turnovers after the catalyst was recycled five times.
HOMOLOGATION OF N-ALKANES USING DIAZOESTERS AND RHODIUM(III)PORPHYRINS. ENHANCED ATTACK ON PRIMARY C-H BONDS.
Callot, H.J.,Metz, F.
, p. 4321 - 4324 (2007/10/02)
Carbethoxycarbene, from ethyl diazoacetate and rhodium(III)porphyrins, inserted into methyl C-H bonds of n-alkenes (C6 to C12) with yields up to 20-25 percent corresponding to a large increase of the primary/secondary selectivity.
