860640-03-5

Basic information

• Product Name: Trifluoro-methanesulfonic acid (2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-ethylsulfanyl-tetrahydro-pyran-3-yl ester
• Synonyms: Trifluoro-methanesulfonic acid (2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-ethylsulfanyl-tetrahydro-pyran-3-yl ester
• CAS NO: 860640-03-5
• Molecular Weight: 665.708
• Mol File: 860640-03-5.mol

Chemical Properties

• CAS DataBase Reference: Trifluoro-methanesulfonic acid (2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-ethylsulfanyl-tetrahydro-pyran-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Trifluoro-methanesulfonic acid (2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-ethylsulfanyl-tetrahydro-pyran-3-yl ester(860640-03-5)
• EPA Substance Registry System: Trifluoro-methanesulfonic acid (2R,3S,4R,5R,6S)-4-benzyloxy-2-benzyloxymethyl-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-ethylsulfanyl-tetrahydro-pyran-3-yl ester(860640-03-5)

Safety Data

• Hazardous Substances Data: 860640-03-5(Hazardous Substances Data)

Upstream product

• 123212-53-3 ethyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-2-N-phthalamido-1-thio-β-D-glucopyranoside 
• 100-39-0 benzyl bromide 
• 99409-33-3 ethyl 4,6-O-benzylidene-2-deoxy-2-N-phthalamido-1-thio-β-Dglucopyranoside 
• 860640-09-1 2-((2S,3R,4R,6R)-4-Benzyloxy-6-benzyloxymethyl-2-ethylsulfanyl-5-oxo-tetrahydro-pyran-3-yl)-isoindole-1,3-dione 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 115533-35-2 ethyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-glucopyranoside 

Downstream Products

• 854911-37-8 ethyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-galactopyranoside 
• 493019-65-1 benzyl O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-galactopyranoside 
• 493019-66-2 benzyl O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-galactopyranoside 
• 493019-68-4 benzyl O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-galactopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-β-D-galactopyranoside 
• 493019-63-9 benzyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-galactopyranoside 
• 493019-64-0 benzyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-galactopyranoside 
• 190247-77-9 ethyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-1-thio-β-D-galactopyranoside 

Relevant articles and documents

Efficient routes to ethyl-2-deoxy-2-phthalimido-1-β-D-thio- galactosamine derivatives via epimerization of the corresponding glucosamine compounds

Short synthetic routes to protected ethyl 2-deoxy-2-phthalimido-1-β-D- thio-galactosamine derivatives via epimerization of the corresponding glucosamine compounds are described. Starting from D-glucosamine hydrochloride, the epimerizations were performed

Synthesis and inhibitory activity of a di- and a trisaccharide corresponding to an erythrocyte glycolipid responsible for the nor polyagglutination

The polyagglutinable erythrocytes NOR contain unusual neutral glycolipids reactive with anti-NOR antibodies. The disaccharide α-D-Galp-(1→4)-D-GalpNAc and the trisaccharide α-D-Galp-(1→4)-β-D-GalpNAc-(1→3)-D-Gal corresponding to the non-reducing end of a NOR glycolipid (NOR1) were chemically synthesized. The syntheses were based on a common (1→4)-β-D-GalNAc precursor, and utilized benzyl glycoside and benzyl ether functions for persistent blocking of hydroxyls. The α-D-Galp-(1→4)-β-D-GalpNAc structural element has been found only recently in Nature, and derivatives thereof have not been synthesized before. Both the synthesized oligosaccharides inhibited specifically human anti-NOR antibodies, the trisaccharide being 300 times more active than the disaccharide.