860699-91-8

Upstream product

• 103089-98-1 2-bromo-1-(4''-(methylsulfanyl)phenyl)-2-phenyl-1-ethanone 
• 73242-07-6 2-phenyl-4'-(methylthio)acetophenone 
• 100-68-5 methyl-phenyl-thioether 
• 103-82-2 phenylacetic acid 
• 100-52-7 benzaldehyde 
• 3446-89-7 4-(Methylthio)benzaldehyde 

Downstream Products

• 1429184-71-3 C₁₇H₁₅ClN₂O₂S₂ 
• 1429184-75-7 C₁₇H₁₆N₂O₄S₂ 
• 1429184-72-4 C₁₈H₁₈N₂O₂S₂ 
• 1429184-78-0 C₁₈H₁₈N₂O₄S₂ 
• 1429184-69-9 C₁₇H₁₆N₂O₂S₂ 
• 1429184-66-6 C₁₆H₁₄N₂O₂S₂ 
• 1415020-19-7 C₁₆H₁₄N₂S₂ 

Relevant academic research and scientific papers

2, 3-Diaryl-5-ethylsulfanylmethyltetrahydrofurans as a new class of COX-2 inhibitors and cytotoxic agents

2,3-Diaryl-5-ethylsulfanylmethyltetrahydrofuran-3-ols were designed and synthesized by the allylations of benzoins followed by iodocyclization and nucleophilic replacement reactions with ethanthiol. These molecules exhibit IC50 for COX-2 at 50 over all the 59 human tumor cell lines at μ M concentration. The Royal Society of Chemistry.

Synthesis, cyclooxygenase inhibitory effects, and molecular modeling study of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and -2-alkylsulfonyl-1H- imidazole derivatives

A series of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and 2-alkylsulfonyl-1H-imidazole derivatives were synthesized. All compounds were tested in human blood assay to determine COX-1 and COX-2 inhibitory potency and selectivity. Among the synthesize