860749-92-4

Upstream product

• 75-15-0 carbon disulfide 
• 2038-57-5 3-Phenylpropan-1-amine 
• 645-59-0 dihydrocinnamonitrile 
• 861572-97-6 μ-disulfido-1,2-dithio-dicarbonic acid bis-(3-phenyl-propylamide) 
• 2627-27-2 3-phenylpropyl isothiocyanate 

Relevant academic research and scientific papers

Rapid and highly efficient synthesis of thioureas in biocompatible basic choline hydroxide

A straightforward and convenient synthesis of symmetrical thiourea derivatives by the reaction of primary amines and carbon disulfide in biocompatible basic choline hydroxide is presented. A variety of biologically important thiourea derivatives can be obtained in good to excellent yields without a tedious work-up under mild reaction conditions. A series of primary aliphatic and aromatic amines with different substituted functional groups have been converted to thiourea derivatives under milder reaction conditions and short reaction times.

Convenient synthesis of 5-arylidene-2-imino-4-thiazolidinone derivatives using microwave irradiation

A concise approach for the preparation of 5-arylidene-2-imino-4- thiazolidinone derivatives is described. Structurally diverse amines, isothiocyanates, aldehydes, and chloroacetyl chloride were combined under microwave irradiation to afford new 5-arylidene-2-imino-4-thiazolidinone derivatives. The one-pot synthesis involves the in situ formation of a thiourea followed by reaction with chloroacetyl chloride and an aldehyde to generate the target compounds. Georg Thieme Verlag Stuttgart New York.