860770-47-4Relevant academic research and scientific papers
Development of a triazolobenzodiazepine-based PET probe for subtype-selective vasopressin 1A receptor imaging
Aravind, Appu,Chen, Jiahui,Haider, Ahmed,Kuang, Shi,Liang, Steven H.,Ramesh, Perla,Ran, Chongzhao,Rong, Jian,Shao, Tuo,Shao, Yihan,Van, Richard S.,Xia, Xiaotian,Xiao, Zhiwei,Young, Larry J.,Zhao, Chunyu
, (2021/09/28)
Objectives: To enable non-invasive real-time quantification of vasopressin 1A (V1A) receptors in peripheral organs, we sought to develop a suitable PET probe that would allow specific and selective V1A receptor imaging in vitro and in vivo. Methods: We sy
SYNTHESIS OF TRANS-8-CHLORO-5-METHYL-1 -[4-(PYRIDIN-2-YLOXY)-CYCLOHEXYL]-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENE AND CRYTALLINE FORMS THEREOF
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Page/Page column 38; 39, (2015/06/18)
The present invention provides processes to manufacture substituted l-[4-(Pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10b- tetraaza-benzo[e]azulenes. Also disclosed are compounds useful as intermediates in the methods of the invention.
COMPOUNDS USEFUL IN THERAPY
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Page/Page column 35, (2010/02/13)
Compounds of formula (I), or a pharmaceutically acceptable derivative thereof, wherein: X represents NR or O; R represents hydrogen, C1-8 alkyl or SO2[C,1-8 alkyl]; W represents N or CH; Y and Y' independently represent hy
