860772-73-2Relevant academic research and scientific papers
Asymmetric catalysis with substitutionally labile yet stereochemically stable chiral-at-metal iridium(III) complex
Huo, Haohua,Fu, Chen,Harms, Klaus,Meggers, Eric
, p. 2990 - 2993 (2014)
A metal-coordination-based high performance asymmetric catalyst utilizing metal centrochirality as the sole element of chirality is reported. The introduced substitutionally labile chiral-at-metal octahedral iridium(III) complex exclusively bears achiral
Direct Access to Highly Enantioenriched α-Branched Acrylonitriles through a One-Pot Sequential Asymmetric Michael Addition/Retro-Dieckmann/Retro-Michael Fragmentation Cascade
Duchemin, Nicolas,Cattoen, Martin,Gayraud, Oscar,Anselmi, Silvia,Siddiq, Bilal,Buccafusca, Roberto,Daumas, Marc,Ferey, Vincent,Smietana, Michael,Arseniyadis, Stellios
supporting information, p. 5995 - 6000 (2020/08/28)
A highly enantioselective synthesis of α-branched acrylonitriles is reported featuring a one-pot sequential asymmetric Michael addition/retro-Dieckmann/retro-Michael fragmentation cascade. The method, which relies on a solid, bench-stable, and commercially available acrylonitrile surrogate, is practical, scalable, and highly versatile and provides a direct access to a wide range of enantioenriched nitrile-containing building blocks. Most importantly, the method offers a new tool to incorporate an acrylonitrile moiety in an asymmetric fashion.
Enantioselective Friedel-Crafts alkylations of α,β-unsaturated 2-acyl imidazoles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes
Evans, David A.,Fandrick, Keith R.,Song, Hyun-Ji
, p. 8942 - 8943 (2007/10/03)
An enantioselective Friedel-Crafts alkylation with α,β-unsaturated 2-acyl imidazoles and electron-rich aromatic nucleophiles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes has been accomplished. These α,β-unsaturated 2-acyl imidazol
