860792-46-7Relevant academic research and scientific papers
Biogenetically inspired enantioselective approach to indolo[2,3-a]- and benzo[a]quinolizidine alkaloids from a synthetic equivalent of secologanin
Bassas, Oriol,Llor, Nuria,Santos, Maria M. M.,Griera, Rosa,Molins, Elies,Amat, Mercedes,Bosch, Joan
, p. 2817 - 2820 (2005)
(Chemical Equation Presented) Racemic oxodiester 1 undergoes stereoselective cyclocondensation with (S)-tryptophanol, (S)-(3,4- dimethoxyphenyl)alaninol, or the corresponding amino acids, in a process involving a tandem dynamic kinetic resolution/desymmetrization of diastereotopic groups, to give bicyclic lactams, which are cyclized to substituted indolo[2,3-a]- and benzo[a]quinolizidines.
Synthesis of 3-acetonyl- and 3-(2-oxoethyl)glutarates
Amat, Mercedes,Bassas, Oriol,Cantó, Margalida,Llor, Núria,Santos, Maria M.M.,Bosch, Joan
, p. 7693 - 7702 (2007/10/03)
Several synthetic routes to 3-acetonyl- and 3-(2-oxoethyl)glutarates 1-5 have been explored. The most advantageous involves, as the key steps, the conjugate addition of an appropriately substituted vinylmagnesium bromide to an alkylidenemalonic ester, a b
