86087-13-0

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 42075-32-1 (2R,4R)-pentanediol 
• 100-52-7 benzaldehyde 

Downstream Products

• 59694-09-6 2,4-pentanediol monobenzoate 
• 124338-54-1 (2R,4R)-2-(benzyloxy)-4-pentanol 
• 88726-11-8 (1S,1'R,3'R)-(3'-hydroxy-1'-methylbutoxy)-1-phenylethane 
• 97949-89-8 (1R,1'R,3'R)-(3'-hydroxy-1'-methylbutoxy)-1-phenylethane 
• 137626-38-1 (2R,4R)-2-(trimethylsiloxy)-4-(benzyloxy)pentane 
• 137626-31-4 (1'R,3'R)-1,1-bis<3'-(benzyloxy)-1'-methylbutoxy>heptane 
• 10020-96-9 (R)-Mandelonitrile 
• 20698-91-3 (R)-methyl mandelate 
• 2549-14-6 (R)-2-Amino-1-phenylethanol 
• 28549-12-4 (S)-mandelonitrile 
• 86013-43-6 (2R,4R)-4-((R)-2-Amino-1-phenyl-ethoxy)-pentan-2-ol 
• 86013-39-0 (R)-((R)-1-Methyl-3-oxo-butoxy)-phenyl-acetonitrile 
• 86013-47-0 [(R)-2-((1R,3R)-3-Hydroxy-1-methyl-butoxy)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 
• 281670-47-1 (S)-(2-hydroxy-2-phenyl-ethyl)carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Graphene-catalyzed transacetalization under acid-free conditions

1,2- and 1,3-Diols are readily protected as cyclic acetals and ketals through a graphene-catalyzed transacetalization process. The methodology features an atom economic procedure since quasi-stoichiometric conditions have been developed. Unlike prior systems, the graphene-catalyzed transacetalization is performed under Br?nsted and Lewis acid-free conditions and without solvent. Our method has been applied to several volatile compounds that are unsuitable for complex work-up and extensive purification steps. The very unusual catalytic properties of graphene for transacetalization reactions are ascribed to molecular charge transfer between graphene and substrates.

Enantioselective route to aryl(1,3-butadien-2-yl)methanols: Formal synthesis of (-)-sporochnol a

Ti(IV)-promoted reaction of the chiral acetals derived from aromatic aldehydes with 1-(tri-n-butyl)stannyl-2,3-butadiene followed by removal of the chiral auxiliary gave aryl(1,3-butadien-2-yl)methanols with high enantiomeric purity (>90% ee). The synthet