86098-03-5Relevant academic research and scientific papers
α-Selective C(sp3)-H Thio/Selenocyanation of Ketones with Elemental Chalcogen
Li, Jin-Cheng,Gao, Wen-Xia,Liu, Miao-Chang,Zhou, Yun-Bing,Wu, Hua-Yue
, p. 17294 - 17306 (2021/12/02)
A facile method is disclosed for the synthesis of α-thio/selenocyanato ketones through regioselective C-H thio/selenocyanation of ketones. The advantages include the use of easily available starting materials, high efficiency, simple operation, and easy scale-up. Control experiments provide evidence that the reaction proceeded via a radical way, while kinetic isotope effect experiments reveal that the cleavage of the C-H bond serves as the rate-limiting step.
Selenocyanation of Aryl and Styryl Methyl Ketones in the Presence of Selenium Dioxide and Malononitrile: An Approach for the Synthesis of α-Carbonyl Selenocyanates
Marpna, Ibakyntiew D.,Wanniang, Kmendashisha,Lipon, Tyrchain Mitre,Shangpliang, O. Risuklang,Myrboh, Bekington
, p. 1980 - 1986 (2021/02/05)
A convenient method has been developed for the synthesis of α-carbonyl selenocyanates from aryl methyl ketones/styryl methyl ketones using selenium dioxide as the selenating agent under simple reaction conditions. This reaction has notable advantages over the traditional methods in terms of accessibility and affordability of the starting materials. The method features the interaction of aryl methyl ketones/styryl methyl ketones with selenium dioxide and malononitrile to afford a series of α-carbonyl selenocyanates in moderate to good yields.
Oxidative umpolung selenocyanation of ketones and arenes: An efficient protocol to the synthesis of selenocyanates
Cui, Jianguo,Wei, Meizhen,Pang, Liping,Xiao, JunAn,Gan, Chunfang,Guo, Jiali,Xie, Chuanfang,Zhu, Qiming,Huang, Yanmin
, (2020/02/06)
A practical method for the umpolung selenocyanation of aryl ketones, alkyl ketones, β-ketoesters and electron-rich arenes has been developed, affording various selenocyanates in moderate to excellent yields. This transformation proceeds by an oxidative um
A novel metal-free method for the selenocyanation of aromatic ketones to afford α-carbonyl selenocyanates
Sun, Kai,Lv, Yunhe,Chen, Yao,Zhou, Tingting,Xing, Yanyan,Wang, Xin
supporting information, p. 4464 - 4467 (2017/07/10)
A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared α-halo ketones, providing rapid access to α-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.
A facile CAN-mediated synthesis of selenocyanates from arylalkenes and heteroarenes
Nair, Vijay,Augustine, Anu,George, Tesmol G.
, p. 2363 - 2366 (2007/10/03)
Selenocyanation of styrenes and indoles mediated by cerium(IV) ammonium nitrate (CAN) afforded the corresponding selenocyanates in moderate to good yields. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
