86098-63-7Relevant academic research and scientific papers
Methylenecyclopropane Ring Formation/Opening Cascade for the Synthesis of Indolizines
Zhu, Congjun,Zhao, Peng,Qiao, Yan,Xiao, Ke,Song, Chuanjun,Chang, Junbiao
, p. 7045 - 7049 (2017)
A unique strategy toward the synthesis of polysubstituted indolizines has been developed. When 2-pyridinyl-2-(2′-bromoallyl)-1-carboxylates were treated with Cs2CO3, the starting material went through a methylenecyclopropane ring formation/opening cascade, and the corresponding indolizines were obtained in moderate to good yield as a single regioisomer.
ONE-POT SYNTHESIS OF FURAN SYSTEM BEARING 2-PYRIDYL SUBSTITUENT
Tsuge, Otohiko,Matsuda, Koyo,Kanemasa, Shuji
, p. 593 - 596 (2007/10/02)
The reaction of an anionic intermediate, generated in situ from the lithio derivative of 2-(trimethylsilylmethyl)pyridine and an aromatic nitrile, with α-haloketones such as phenacyl bromide, desyl chloride and 2-bromocyclohexanone provided a route to a one-pot synthesis of rare 2-pyridyl substituted furans.The reaction pathway is also described.
