6298-46-0

Basic information

• Product Name: N-[2-(3,4-diethoxyphenyl)ethyl]-2-(3,4-diethoxyphenyl)acetamide
• Synonyms: N-[2-(3,4-diethoxyphenyl)ethyl]-2-(3,4-diethoxyphenyl)acetamide;N-[2-(3,4-Diethoxyphenyl)ethyl]-3,4-diethoxybenzeneacetamide;Einecs 228-573-4
• CAS NO: 6298-46-0
• Molecular Formula: C₂₄H₃₃NO₅
• Molecular Weight: 415.52252
• EINECS: 228-573-4
• Mol File: 6298-46-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 595°C at 760 mmHg
• Flash Point: 313.6°C
• Appearance: /
• Density: 1.082g/cm³
• Vapor Pressure: 4.01E-14mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: N-[2-(3,4-diethoxyphenyl)ethyl]-2-(3,4-diethoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3,4-diethoxyphenyl)ethyl]-2-(3,4-diethoxyphenyl)acetamide(6298-46-0)
• EPA Substance Registry System: N-[2-(3,4-diethoxyphenyl)ethyl]-2-(3,4-diethoxyphenyl)acetamide(6298-46-0)

Safety Data

• Hazardous Substances Data: 6298-46-0(Hazardous Substances Data)

Usage

Uses

N-[2-(3,4-Diethoxyphenyl)ethyl]-3,4-diethoxybenzeneacetamide is an impurity/degradation product of drotaverine(D689700); an antispasmodic.

InChI:InChI=1/C24H33NO5/c1-5-27-20-11-9-18(15-22(20)29-7-3)13-14-25-24(26)17-19-10-12-21(28-6-2)23(16-19)30-8-4/h9-12,15-16H,5-8,13-14,17H2,1-4H3,(H,25,26)

Upstream product

• 61381-04-2 2-(3,4-diethoxyphenyl)ethylamine 
• 38464-04-9 3,4-diethoxy-phenyl-acetic acid 
• 53017-34-8 ethyl 2-(3,4-diethoxyphenyl)-2-oxoacetate 
• 2050-46-6 1,2-diethoxybenzene 
• 1137-71-9 1-(3,4-diethoxyphenyl)ethanone 
• 526190-09-0 2-(3,4-diethoxyphenyl)acetamide 
• 92157-09-0 methyl 2-(3,4-diethoxyphenyl)acetate 
• 69373-87-1 ethyl 2-(3,4-diethoxyphenyl)acetate 
• 1005009-95-9 2-(3,4-diethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 279262-08-7 3,4-diethoxyphenylboronic acid 
• 53207-08-2 4-bromo-1,2-diethoxybenzene 
• 17345-77-6 1-bromo-3,4-dihydroxybenzene 

Downstream Products

• 861-27-8 1-(3',4'-diethoxy-benzyl)-6,7-diethoxy-3,4-dihydro-isoquinoline 
• 985-12-6 1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 
• 486-47-5 ethaverine 

Relevant articles and documents

Novel method for preparing drotaverine hydrochloride intermediate

The invention discloses a novel method for preparing a drotaverine hydrochloride intermediate, belonging to the technical field of medicine synthesis. The preparation method comprises the following steps: preparing an intermediate 3,4-diethoxyphenylacetic acid with 1,2-diethoxybenzene as a raw material, and preparing the intermediate 3,4-diethoxyphenylacetamide with 3,4-diethoxyphenylacetic acid as a raw material. According to the novel process for preparing the drotaverine hydrochloride intermediate, a method for directly preparing 3,4-diethoxyphenylacetic acid and 3,4-diethoxyphenylethylamine is adopted, and a process for preparing 3,4-diethoxyphenylacetonitrile is avoided, so a reaction step of using sodium cyanide is avoided.