86100-06-3Relevant academic research and scientific papers
Copper-catalyzed cyclization of 3-acylcoumarin hydrazone using air as the oxidant: Efficient synthesis of pyrazole-fused coumarin derivatives
Wang, Hui-Yan,Liu, Xue-Cheng,Huang, Zhi-Bin,Shi, Da-Qing
, p. 380 - 385 (2015/03/30)
An efficient, convenient Cu-catalyzed formation of chromeno[4,3-c]pyrazol-4(1H)-ones is reported. In this atom economic process, readily available 3-acylcoumarin hydrazone is oxidative cyclized by direct C-N bond formation. Air has been successfully used
Synthesis, biological evaluation and docking analysis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones as potential cyclooxygenase-2 (COX-2) inhibitors
Grover, Jagdeep,Kumar, Vivek,Sobhia, M. Elizabeth,Jachak, Sanjay M.
, p. 4638 - 4642 (2015/01/09)
As a part of our continued efforts to discover new COX inhibitors, a series of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones were synthesized and evaluated for in vitro COX inhibitory potential. Within this series, seven compounds (3a-d, 3h, 3k and 3
Microwave-assisted synthesis of 3-methyl-1-phenyl-chromeno[4,3-c]pyrazol- 4(1H)-ones under solvent-free conditions
Yang, Guo-Yu,Yang, Jing-Tian,Wang, Cai-Xia,Fan, Su-Fang,Xie, Pu-Hui,Xu, Cui-Lian
, p. 1327 - 1336 (2013/07/19)
A novel microwave-assisted method for the synthesis of 3-methyl-1- phenylchromeno[4,3-c]pyrazol-4(1H)-ones by the cyclization of 3-[1-(phenylhydrazono)ethyl]chromen-2-ones with CuO/SBA-15 under solvent-free conditions is described. The reaction gave the c
Study on the cyclization methods of 3-[1-(phenyl-hydrazono)ethyl]-chromen- 2-ones
Yang, Guo-Yu,Wang, Cai-Xia,Fan, Su-Fang,Zhao, Long-Jie,Wang, Dan,Xu, Cui-Lian
, p. 1263 - 1269 (2013/03/28)
Some new methods, such as air oxidation, catalytic oxidation, and solvent-free synthesis, are developed for the synthesis of 3-methyl-1- phenylchromeno[4,3-c]pyrazol-4(1H)-ones(2) from the cyclization of 3-[1-(phenyl-hydrazono)ethyl]-chromen-2-ones(1). Co
X-ray supramolecular structure, NMR spectroscopy and synthesis of 3-methyl-1-phenyl-1H-chromeno[4,3-c]pyrazol-4-ones formed by the unexpected cyclization of 3-[1-(phenylhydrazono)ethyl]-chromen-2-ones
Padilla-Martinez, Itzia I.,Flores-Larios, Irma Y.,Garcia-Baez, Efren V.,Gonzalez, Jorge,Cruz, Alejandro,Martinez-Martinez, Francisco J.
, p. 915 - 932 (2011/04/18)
The molecular structures of nine 3-methyl-1-phenyl-1H-chromeno[4,3-c] pyrazol-4-one isomers, obtained by the oxidative cyclization of the corresponding 1-phenylhydrazono chromen-2-ones with copper acetate as catalyst, are reported. The molecular and supra
