861108-19-2

Upstream product

• 637-89-8 4-sulfanylphenol 
• 861108-20-5 C₂₉H₄₂O₅S₂Sn 
• 5656-44-0 4-(allylthio)phenol 
• 861108-17-0 methyl 2-(4-{4-[(2-oxiranylpropyl)sulfonyl]phenoxy}phenyl)acetate 
• 861108-15-8 methyl 2-{4-[4-(allylthio)phenoxy]phenyl}acetate 
• 861108-18-1 methyl 2-(4-{4-[(2-thiiranylpropyl)sulfonyl]phenoxy}phenyl)acetate 

Downstream Products

• 915155-69-0 C₂₄H₂₂O₅S₂ 
• 915155-65-6 C₂₄H₂₁ClO₅S₂ 
• 1027206-70-7 C₂₂H₂₀O₅S₃ 
• 915155-68-9 C₂₃H₂₁NO₅S₂ 
• 915155-67-8 C₂₃H₂₁NO₅S₂ 
• 915155-73-6 C₂₂H₂₁NO₅S₂ 
• 915155-75-8 C₂₃H₂₂N₂O₄S₂ 
• 915155-74-7 C₂₃H₂₂N₂O₄S₂ 
• 915155-72-5 C₂₄H₂₃NO₄S₂ 
• 915155-71-4 C₂₁H₂₅NO₄S₂ 
• 915155-64-5 C₂₁H₂₄O₅S₂ 

Relevant academic research and scientific papers

INHIBITORS OF MATRIX METALLOPROTEINASES

The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.

Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A

Matrix metalloproteinases (MMPs), of which 26 are known, have been implicated in a number of pathological conditions, including tumor metastasis. We have previously described the first mechanism-based inhibitor for MMPs (J. Am. Chem. Soc. 2000, 122, 6799-