861208-16-4Relevant academic research and scientific papers
Microwave-assisted one-pot synthesis of substituted 3-bromoimidazo[1,2 -A]pyridines and imidazoheterocycles
Patil, Shashikant M.,Mascarenhas, Malcolm,Sharma, Rajiv,Mohana Roopan,Roychowdhury, Abhijit
, p. 1509 - 1515 (2015)
Herein, an efficient, one-pot microwave-assisted synthesis of a diverse set of 3-bromoimidazo[1,2-a]pyridines is being reported with good yields (40-85%). The method involves electrophilic aromatic bromination using bromodimethylsulfonium ion generated in situ via oxidation of HBr salt by DMSO. This methodology was also applied to the synthesis of related imidazoheterocycles.
