86136-89-2Relevant academic research and scientific papers
M-CPBA-Mediated Intramolecular Aminohydroxylation of N-Sulfonyl Aminoalkenes to Synthesize β-Hydroxyl Cyclic Amines
Yin, Yan,Zhou, Hong,Sun, Guofeng,Liu, Xichen
, p. 1337 - 1345 (2015/10/06)
A variety of structurally diverse N-sulfonyl-protected aminoalkenes readily reacted with m-CPBA to produce a series of β-hydroxyl cyclic amines in high yields through intramolecular aminohydroxylation. This metal-free and easy-to-handle synthetic methodol
Asymmetric indoline synthesis via intramolecular aza-Michael addition mediated by bifunctional organocatalysts
Miyaji, Ryota,Asano, Keisuke,Matsubara, Seijiro
, p. 3658 - 3661 (2013/08/23)
A novel method for the asymmetric synthesis of 2-substituted indolines, employing bifunctional amino(thio)urea catalysts, was developed. The reaction proceeded via an intramolecular aza-Michael addition mediated by activation through hydrogen bonding. The
Organocatalytic approach to benzofused nitrogen-containing heterocycles: Enantioselective total synthesis of (+)-angustureine
Fustero, Santos,Moscardo, Javier,Jimenez, Diego,Perez-Carrion, Maria Dolores,Sanchez-Rosello, Maria,Del Pozo, Carlos
supporting information; experimental part, p. 9868 - 9872 (2009/10/20)
A study was conducted to demonstrate an organocatalytic approach to benzofused nitrogen-containing heterocycles. he study also demonstrated enantioselective total synthesis of (+)-angustureine. It reported the easy an d enantioselective preparation of tet
Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: Enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid
Carlson, Erik C.,Rathbone, Lauren K.,Yang, Hua,Collett, Nathan D.,Carter, Rich G.
, p. 5155 - 5158 (2008/09/21)
(Chemical Equation Presented) An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and piperidine rings using an organocatalyzed, intramolecular heteroatom Michael addition is described. Application to the enantioselective synthesis of homoproline, homopipecolic acid, and pelletierine has been accomplished.
Gold(I)-catalyzed intramolecular hydroamination of alkenyl carbamates
Han, Xiaoqing,Widenhoefer, Ross A.
, p. 1747 - 1749 (2007/10/03)
(Chemical Equation Presented) Gold for rings: Reaction of alkenyl carbamates such as 1 in the presence of [Au{P(tBu)2(o-biphenyl)}]Cl and AgOTf led to nitrogen heterocycles (e.g. 2). This AuI-catalyzed intramolecular hydroamination t
Construction of nitrogen-heterocyclic compounds through zirconium mediated intramolecular alkene-carbonyl coupling reaction of N-(o-alkenylaryl)carbamate derivatives
Takigawa, Yasushi,Ito, Hisanaka,Omodera, Katsunori,Ito, Maiko,Taguchi, Takeo
, p. 1385 - 1392 (2007/10/03)
Intramolecular alkene-carbonyl coupling reaction of N-benzyl-N-(o- alkenylaryl)carbamate derivative derived from o-aminostyrene, o-(aminomethyl)styrene and o-aminoallylbenzene smoothly proceeded by treating with zirconocene-butene complex to give the corresponding lactam derivative.
